{"id":2129,"date":"2022-04-08T01:19:43","date_gmt":"2022-04-08T01:19:43","guid":{"rendered":"https:\/\/smasteer.wpengine.com\/what-to-expect\/"},"modified":"2023-04-05T16:17:34","modified_gmt":"2023-04-05T16:17:34","slug":"what-to-expect","status":"publish","type":"page","link":"https:\/\/thesteerstudy.com\/za-en\/what-to-expect\/","title":{"rendered":"What to expect"},"content":{"rendered":"<p>[vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;1&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;193723&#8243;][vc_column width=&#8221;1\/1&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; uncode_shortcode_id=&#8221;102227&#8243; subheading=&#8221;The study lasts up to 72 weeks (up to 17 months) with 29 visits for tests and 2 hospital stays.&#8221;]What happens during the study?[\/vc_custom_heading][vc_single_image media=&#8221;85&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;105576&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;2&#8243; bottom_padding=&#8221;4&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;154932&#8243;][vc_column width=&#8221;2\/3&#8243;][vc_column_text uncode_shortcode_id=&#8221;587747&#8243;]*At the end of the study, your child will have the option to enrol in a long-term follow-up study in which your child\u2019s health will be monitored for an additional 15 years.[\/vc_column_text][vc_button button_color=&#8221;color-jevc&#8221; size=&#8221;btn-lg&#8221; border_animation=&#8221;btn-ripple-out&#8221; outline=&#8221;yes&#8221; border_width=&#8221;2&#8243; button_color_type=&#8221;uncode-palette&#8221; uncode_shortcode_id=&#8221;152205&#8243; link=&#8221;url:https%3A%2F%2Fsmasteer.wpengine.com%2F%23participate|&#8221;]Who can join?[\/vc_button][\/vc_column][vc_column width=&#8221;1\/3&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;7&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; back_color=&#8221;color-914595&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;198236&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column width=&#8221;1\/1&#8243;][vc_single_image media=&#8221;3181&#8243; media_width_percent=&#8221;90&#8243; alignment=&#8221;center&#8221; uncode_shortcode_id=&#8221;105385&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;4&#8243; back_color=&#8221;color-914595&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;106647&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;5\/12&#8243; uncode_shortcode_id=&#8221;183673&#8243;][vc_single_image media=&#8221;87&#8243; media_width_use_pixel=&#8221;yes&#8221; alignment=&#8221;center&#8221; uncode_shortcode_id=&#8221;166811&#8243; media_width_pixel=&#8221;200&#8243;][\/vc_column][vc_column column_width_percent=&#8221;95&#8243; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;7\/12&#8243; uncode_shortcode_id=&#8221;763803&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; uncode_shortcode_id=&#8221;227058&#8243; subheading=&#8221;Before starting the study, you will need to give permission for your child to join by reading and signing an Informed Consent Form. Depending on their age, some children may also give permission by signing an Informed Assent Form. The study doctor will then collect information and run tests to make sure the study is right for your child.&#8221;]Screening[\/vc_custom_heading][vc_button button_color=&#8221;color-jevc&#8221; size=&#8221;btn-lg&#8221; border_animation=&#8221;btn-ripple-out&#8221; outline=&#8221;yes&#8221; border_width=&#8221;2&#8243; button_color_type=&#8221;uncode-palette&#8221; uncode_shortcode_id=&#8221;202159&#8243; link=&#8221;url:%23tests|&#8221;]Other tests[\/vc_button][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;2&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;139417&#8243;][vc_column width=&#8221;1\/1&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; uncode_shortcode_id=&#8221;480260&#8243; subheading=&#8221;The study has 2 treatment periods along with 2 follow-up periods:&#8221;]Treatment and Follow-up[\/vc_custom_heading][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;2&#8243; bottom_padding=&#8221;2&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;181455&#8243;][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;417798&#8243;][vc_single_image media=&#8221;88&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;175841&#8243;][\/vc_column][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;154477&#8243;][vc_single_image media=&#8221;91&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;208200&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;0&#8243; back_color=&#8221;color-914595&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;137887&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;92&#8243; media_width_percent=&#8221;60&#8243; alignment=&#8221;center&#8221; uncode_shortcode_id=&#8221;774214&#8243;][\/vc_column][vc_column column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;254054&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; uncode_shortcode_id=&#8221;231480&#8243; subheading=&#8221;OAV101 is given as a one-time injection into the lower part of the spine (intrathecal injection).&#8221;]How is OAV101 given?[\/vc_custom_heading][vc_button button_color=&#8221;color-jevc&#8221; size=&#8221;btn-lg&#8221; border_animation=&#8221;btn-ripple-out&#8221; outline=&#8221;yes&#8221; border_width=&#8221;2&#8243; button_color_type=&#8221;uncode-palette&#8221; uncode_shortcode_id=&#8221;166297&#8243; link=&#8221;url:https%3A%2F%2Fsmasteer.wpengine.com%2F%23what-is|&#8221;]What is OAV101?[\/vc_button][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;2&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;208227&#8243; row_name=&#8221;tests&#8221;][vc_column width=&#8221;1\/1&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; uncode_shortcode_id=&#8221;320528&#8243; subheading=&#8221;Some of the tests your child will have during the study include:&#8221;]What kind of tests will my child have?[\/vc_custom_heading][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;138062&#8243;][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;439732&#8243;][vc_gallery el_id=&#8221;gallery-392723&#8243; isotope_mode=&#8221;fitRows&#8221; medias=&#8221;94,95,96,97,98,99,100,101,102,103,93&#8243; gutter_size=&#8221;3&#8243; media_items=&#8221;media|nolink|original,title&#8221; screen_lg=&#8221;1400&#8243; screen_md=&#8221;1000&#8243; screen_sm=&#8221;800&#8243; single_text=&#8221;under&#8221; single_width=&#8221;2&#8243; images_size=&#8221;one-one&#8221; single_overlay_opacity=&#8221;50&#8243; single_overlay_anim=&#8221;no&#8221; single_text_visible=&#8221;yes&#8221; single_text_anim=&#8221;no&#8221; single_image_anim=&#8221;no&#8221; single_h_align=&#8221;center&#8221; single_v_position=&#8221;top&#8221; single_padding=&#8221;2&#8243; single_title_family=&#8221;font-555555&#8243; single_title_dimension=&#8221;h4&#8243; single_border=&#8221;yes&#8221; uncode_shortcode_id=&#8221;241942&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;2&#8243; bottom_padding=&#8221;4&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;697365&#8243;][vc_column width=&#8221;2\/3&#8243;][vc_column_text uncode_shortcode_id=&#8221;135387&#8243;]*Mental health check may not apply to children younger than 7 years.<\/p>\n<p>These are only some of the tests that will take place during the study. Your child will not have all of the tests at each visit. Talk to the study doctor for more information.<\/p>\n<p>Carers will also be asked to fill out a questionnaire about how their child\u2019s SMA affects their everyday life.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;1&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;193723&#8243;][vc_column width=&#8221;1\/1&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; uncode_shortcode_id=&#8221;102227&#8243; subheading=&#8221;The study lasts [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":83,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-2129","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/pages\/2129","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/comments?post=2129"}],"version-history":[{"count":0,"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/pages\/2129\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/media\/83"}],"wp:attachment":[{"href":"https:\/\/thesteerstudy.com\/za-en\/wp-json\/wp\/v2\/media?parent=2129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}