{"id":2168,"date":"2022-04-08T00:34:48","date_gmt":"2022-04-08T00:34:48","guid":{"rendered":"https:\/\/smasteer.wpengine.com\/about-the-study\/"},"modified":"2022-07-19T21:21:15","modified_gmt":"2022-07-19T21:21:15","slug":"about-the-study","status":"publish","type":"page","link":"https:\/\/thesteerstudy.com\/my-en\/","title":{"rendered":"About The Study"},"content":{"rendered":"<p>[vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;325473&#8243; row_name=&#8221;what-is&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_custom_heading text_size=&#8221;h1&#8243; text_height=&#8221;fontheight-181378&#8243; uncode_shortcode_id=&#8221;269975&#8243; subheading=&#8221;The purpose of the STEER Study is to understand if the investigational gene therapy OAV101 is safe and can help improve muscle function in children aged 2 to less than 18 years with Type 2 spinal muscular atrophy (SMA).&#8221;]What is the purpose of the STEER Study?[\/vc_custom_heading][vc_button button_color=&#8221;color-jevc&#8221; size=&#8221;btn-lg&#8221; radius=&#8221;btn-round&#8221; border_animation=&#8221;btn-ripple-out&#8221; outline=&#8221;yes&#8221; border_width=&#8221;2&#8243; button_color_type=&#8221;uncode-palette&#8221; uncode_shortcode_id=&#8221;156485&#8243; link=&#8221;url:%23participate|&#8221;]Who can join?[\/vc_button][vc_single_image media=&#8221;76&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;128483&#8243;][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_custom_heading text_size=&#8221;h1&#8243; text_height=&#8221;fontheight-181378&#8243; uncode_shortcode_id=&#8221;163679&#8243; subheading=&#8221;OAV101 is a gene therapy designed to deliver a new functioning copy of the SMN1 gene to the motor neurons. The goal is for the new SMN1 gene to make enough SMN protein to prevent further loss of motor neurons.&#8221;]What is OAV101?[\/vc_custom_heading][vc_single_image media=&#8221;200&#8243; media_width_percent=&#8221;90&#8243; alignment=&#8221;center&#8221; uncode_shortcode_id=&#8221;194517&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; back_color=&#8221;color-914595&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;410730&#8243; back_color_type=&#8221;uncode-palette&#8221; row_name=&#8221;participate&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;79&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;107057&#8243;][\/vc_column][vc_column column_width_percent=&#8221;90&#8243; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;136271&#8243;][vc_custom_heading text_size=&#8221;h1&#8243; text_height=&#8221;fontheight-181378&#8243; uncode_shortcode_id=&#8221;125477&#8243; subheading=&#8221;The study is for children aged 2 to less than 18 years old with Type 2 spinal muscular atrophy (SMA) who:&#8221;]Who can participate in this study?[\/vc_custom_heading][uncode_list uncode_shortcode_id=&#8221;237932&#8243;]<\/p>\n<ul>\n<li>\u2022 Are able to sit independently but have never been able to walk independently.<\/li>\n<li>\u2022 Began showing symptoms of spinal muscular atrophy (SMA) at 6 months of age or older.<\/li>\n<li>\u2022 Have not yet received any treatments that increase SM N.<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;325473&#8243; row_name=&#8221;what-is&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_custom_heading text_size=&#8221;h1&#8243; text_height=&#8221;fontheight-181378&#8243; uncode_shortcode_id=&#8221;269975&#8243; subheading=&#8221;The purpose [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":2716,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-2168","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/pages\/2168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/comments?post=2168"}],"version-history":[{"count":0,"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/pages\/2168\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/media\/2716"}],"wp:attachment":[{"href":"https:\/\/thesteerstudy.com\/my-en\/wp-json\/wp\/v2\/media?parent=2168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}